Nicotinic Mechanisms Modulate Ethanol Withdrawal and Modify Time Course and Symptoms Severity of Simultaneous Withdrawal from Alcohol and Nicotine
INTRODUCTION
Alcohol use disorder is a major cause of economical and
societal problems. Up to 4% of yearly deaths worldwide can be
attributed to alcohol use (WHO, 2011). In the United States,
health care-related costs because of alcoholism surpass those
of cancer and obesity (CASA, 2000). Alcohol and tobacco
co-abuse is common.
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